Experimental model of induction of diabetes mellitus in rats

EN Carvalho, NAS Carvalho, LM Ferreira - Acta Cirurgica Brasileira, 2003 - SciELO Brasil
Diabetes mellitus is a potentially morbid condition with high prevalence worldwide, thus being
a major medical concern. Experimental models … a rat diabetes mellitus model induced by …

[PDF][PDF] Evidence based analysis of chemical method of induction of diabetes mellitus in experimental rats

EU Etuk, BJ Muhammed - Int J Res Pharm Sci, 2010 - researchgate.net
… by chemical agent (alloxan) and oral glucose loading in experimental rats, and their … of
chemical induction as a model for studying type 2 diabetes mellitus in experimental animals. …

Current methods of the modeling of experimental diabetes mellitus type 2: a literature review

YM Kolesnyk, TV Ivanenko, AV Abramov, NV Kuzo - Патологія, 2016 - irbis-nbuv.gov.ua
… Using the experimental models gives the possibility to assess the significance of the activity
… and common experimental models of diabetes mellitus type 2 (T2DM) in small rodents and …

[PDF][PDF] Animals models for studying diabetes mellitus

EU Etuk - Agric Biol JN Am, 2010 - Citeseer
… and the most practicable method of inducing diabetes mellitus in rodents. … experimental
models developed for studying diabetes mellitus, assess the merits and demerits of each model

Experimental diabetes mellitus in different animal models

A Al-Awar, K Kupai, M Veszelka… - Journal of diabetes …, 2016 - Wiley Online Library
… Sevoflurane postconditioning was abolished by chemically induced diabetes in a rat model
and this detrimental effect involved the impairment of phosphorylation of glycogen synthase …

[PDF][PDF] A new model for alloxan-induced diabetes mellitus in rats

OL Sheriff, O Olayemi, AO Taofeeq… - Journal of …, 2019 - researchgate.net
… is widely used to induce experimental diabetes mellitus (DM) in … experimental models
for this pathological condition4. … compound used to induce experimental diabetes due to its …

Streptozotocin–nicotinamide-induced diabetes in the rat. Characteristics of the experimental model

T Szkudelski - Experimental biology and medicine, 2012 - journals.sagepub.com
… -cells and characterizes the experimental model of diabetes induced by administration of
these … (GK) rats, a non-obese model of type 2 diabetes. In type 2 diabetic patients with reduced …

The effects of dosage and the routes of administrations of streptozotocin and alloxan on induction rate of typel diabetes mellitus and mortality rate in rats

A Mostafavinia, A Amini, SK Ghorishi… - Laboratory animal …, 2016 - Springer
… of administration to imply minimum mortality rate and high incidence of diabetes mellitus (OM)
in the rat experiment model. Rats were randomly divided into STZ, Alloxan and control …

Diabetes mellitus and anal sphincter pressures: an experimental model in rats

HS Fillmann, S Llessuy, CA Marroni… - Diseases of the colon & …, 2007 - Springer
… -induced diabetic rats, we used an … diabetic rats with sphincter hypotony 60 days after
induction. After administration, we observed a significant increase in the anal pressures of diabetic

[PDF][PDF] Animal model used for experimental study of diabetes mellitus: an overview

P Sharma, A Garg, S Garg, V Singh - Asian J Biomat Res, 2016 - researchgate.net
… In this approach, single dose of STZ to the neonatal rat induces Type-2 diabetes, the single
dose of STZ 100 mg/kg ip to the one day old pup and 120 mg/kg ip to the two, three, or five …