Exploration of the Germline Genome of the Ciliate Chilodonella uncinata through Single-Cell Omics (Transcriptomics and Genomics)
Separate germline and somatic genomes are found in numerous lineages across the
eukaryotic tree of life, often separated into distinct tissues (eg, in plants, animals, and fungi)
or distinct nuclei sharing a common cytoplasm (eg, in ciliates and some foraminifera). In
ciliates, germline-limited (ie, micronuclear-specific) DNA is eliminated during the
development of a new somatic (ie, macronuclear) genome in a process that is tightly linked
to large-scale genome rearrangements, such as deletions and reordering of protein-coding …
eukaryotic tree of life, often separated into distinct tissues (eg, in plants, animals, and fungi)
or distinct nuclei sharing a common cytoplasm (eg, in ciliates and some foraminifera). In
ciliates, germline-limited (ie, micronuclear-specific) DNA is eliminated during the
development of a new somatic (ie, macronuclear) genome in a process that is tightly linked
to large-scale genome rearrangements, such as deletions and reordering of protein-coding …
[PDF][PDF] Exploration of the germline genome of the ciliate Chilodonella uncinata through single-cell omics (transcriptomics and genomics). mBio 9: 01836-17
Separate germline and somatic genomes are found in numerous lineages across the
eukaryotic tree of life, often separated into distinct tissues (eg, in plants, animals, and fungi)
or distinct nuclei sharing a common cytoplasm (eg, in ciliates and some foraminifera). In
ciliates, germline-limited (ie, micronuclear-specific) DNA is eliminated during the
development of a new somatic (ie, macronuclear) genome in a process that is tightly linked
to large-scale genome rearrangements, such as deletions and reordering of protein-coding …
eukaryotic tree of life, often separated into distinct tissues (eg, in plants, animals, and fungi)
or distinct nuclei sharing a common cytoplasm (eg, in ciliates and some foraminifera). In
ciliates, germline-limited (ie, micronuclear-specific) DNA is eliminated during the
development of a new somatic (ie, macronuclear) genome in a process that is tightly linked
to large-scale genome rearrangements, such as deletions and reordering of protein-coding …
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