Introduction Gross and microstructural changes in placental development can influence
placental function and adversely impact fetal growth and well-being; however, there is a
paucity of invivo tools available to reliably interrogate in vivo placental microstructural
development. The objective of this study is to characterize invivo placental microstructural
diffusion and perfusion in healthy and growth-restricted pregnancies (FGR) using non-
invasive diffusion-weighted imaging (DWI). Methods We prospectively enrolled healthy …