[HTML][HTML] Expression and function of CB1 receptor in the rat striatum: localization and effects on D1 and D2 dopamine receptor-mediated motor behaviors

AB Martín, E Fernandez-Espejo, B Ferrer… - …, 2008 - nature.com
Cannabinoid CB 1 receptors are densely expressed on striatal projection neurons
expressing dopamine D 1 or D 2 receptors. However, the specific neuronal distribution of CB
1 receptors within the striatum is not known. Previous research has established that the
endocannabinoid system controls facilitation of behavior by dopamine D 2 receptors, but it is
not clear if endocannabinoids also modulate D 1 receptor-mediated motor behavior. In the
present study, we show that cannabinoid CB 1 receptor mRNA is present in striatonigral …

Expression and function of CB1 receptor in the rat striatum: Localization and effects on D1 and D2 dopamine receptor-mediated motor behaviors

AB Martín-Hernández, E Fernández-Espejo, B Ferrer… - 2008 - digital.csic.es
Cannabinoid CB1 receptors are densely expressed on striatal projection neurons
expressing dopamine D1 or D2 receptors. However, the specific neuronal distribution of
CB1 receptors within the striatum is not known. Previous research has established that the
endocannabinoid system controls facilitation of behavior by dopamine D 2 receptors, but it is
not clear if endocannabinoids also modulate D1 receptor-mediated motor behavior. In the
present study, we show that cannabinoid CB1 receptor mRNA is present in striatonigral …
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