Expression of αVβ3 integrin in rat endometrial epithelial cells and its functional role during implantation

KR Srinivasan, CS Blesson, I Fatima, S Kitchlu… - General and …, 2009 - Elsevier
The αVβ3 integrin as a marker of endometrial receptivity has been well established in
human and other mammalian species; however, its expression is still not known in rats. Our
objective was to establish the expression of αVβ3 integrin as a marker of endometrial
receptivity in rat and to further prove its role in implantation by function-blocking studies in
this species. Immunocytochemical, immunohistochemical and flow-cytometric studies were
performed in rat endometrial epithelial cells (EEC) to demonstrate the expression of αVβ3 …
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