Fabrication of Cr doped SnO 2 nanoparticles based biosensor for the selective determination of riboflavin in pharmaceuticals

N Lavanya, S Radhakrishnan, C Sekar… - Analyst, 2013 - pubs.rsc.org
Analyst, 2013pubs.rsc.org
We report the fabrication and testing of a riboflavin (RF) biosensor based on the use of Cr
doped SnO2 nanoparticles. The Cr–SnO2 nanoparticles with chromium concentration from 0
to 5 wt% were synthesised by a microwave irradiation method. Magnetic studies revealed
that only 3 wt% Cr doped nano-SnO2 has ferromagnetic behaviour at room temperature.
This Cr–SnO2 nanoparticles modified electrode responded to RF linearly over a
concentration range of 0.2× 10− 6 to 1.0× 10− 4 M with a detection limit of 107 nM. The …
We report the fabrication and testing of a riboflavin (RF) biosensor based on the use of Cr doped SnO2 nanoparticles. The Cr–SnO2 nanoparticles with chromium concentration from 0 to 5 wt% were synthesised by a microwave irradiation method. Magnetic studies revealed that only 3 wt% Cr doped nano-SnO2 has ferromagnetic behaviour at room temperature. This Cr–SnO2 nanoparticles modified electrode responded to RF linearly over a concentration range of 0.2 × 10−6 to 1.0 × 10−4 M with a detection limit of 107 nM. The fabricated sensor showed an excellent anti-interference ability against electroactive species and metal ions and proved to be useful for the estimation of the RF content in pharmaceutical samples with satisfactory recovery.
The Royal Society of Chemistry
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