Amphibian skin secretions are abundant in bioactive compounds, especially antimicrobial
peptides. These molecules are generally cationic and rich in hydrophobic amino acids, have
an amphipathic structure and adopt an α-helical conformation when in contact with
microorganisms membranes. In this work, we purified and characterized Figainin 1, a novel
antimicrobial and antiproliferative peptide from the cutaneous secretion of the frog Boana
raniceps. Figainin 1 is a cationic peptide with eighteen amino acid residues—rich in leucine …