Glycans are essential cellular components that facilitate a range of critical functions
important for tissue development and mucosal homeostasis. Furthermore, specific
alterations in glycosylation represent important diagnostic hallmarks of cancer that
contribute to tumor cell dissociation, invasion, and metastasis. However, much less is known
about how glycosylation contributes to the pathobiology of inflammatory mucosal diseases.
Here we will review how epithelial and immune cell glycosylation regulates gut homeostasis …