… Three clinical trials on the use of tamoxifen to prevent breast cancer have reported mixed
results. The overall evidence supports a reduction in the risk of breast cancer, but whether this …

… risk of developing breast cancer were randomly assigned (1:1) to … Long-term results of
tamoxifen prophylaxis for breast cancer–… early and late effects is unclear, but that trial randomly …

… IBIS-I was a randomized controlled trial that investigated the … the IBIS-I trial, experiencing
predefined symptoms in the first … at increased risk of breast cancer resulting from known risk …

… : extended long-term follow-up of the IBIS-I breast cancer prevention trial. … Very few deaths
from breast cancer have occurred to date, but it is too early to expect an effect on this outcome, …

… in an investigation of the use of tamoxifen to prevent breast cancer. This article presents results
for … All had a higher-than-normal risk for developing breast cancer, and all had a baseline …

… from the International Breast Cancer Intervention Studies [IBIS-I (… In this analysis of two
large randomised preventive therapy … in both IBIS-I and IBIS-II cohorts, likely resulting in higher …

… than 6 months (unless as part of IBIS-I and treatment was completed at least 5 years before
… of breast cancer in the first 7 years of follow-up in women at high risk. Our results are similar …

… first results of the ATAC trial in the treatment of early breast … first-line therapy for advanced
breast cancer in postmenopausal … : results of a North American multicenter randomized trial. J …

… The IBIS-I trial remains blinded after the initial report, and here we report efficacy results …
was detected at the same hospital through which they participated in the IBIS-I study. In addition, …

… First events were further categorised as local recurrence (all ipsilateral disease), distant …
Exclusion of these women from the primary analysis did not alter the results (data not shown…