Background Cholera, an acute enteric infection, is a serious health challenge in both the
underdeveloped and the developing world. It is caused by Vibrio cholerae after ingestion of
fecal contaminated food or water. Cholera outbreaks have recently been observed in
regions facing natural calamities (ie, earthquake in Haiti 2010) or war (ie, ongoing civil war
in Yemen 2016) where healthcare and sanitary setups have been disrupted as a
consequence. Whole-cell oral cholera vaccines (OCVs) have been in market but their …