Evidence that circadian food-anticipatory activity and temperature rhythms are absent in
Bmal1 knockout mice and rescued by restoration of Bmal1 expression selectively in the
dorsomedial hypothalamus was published in 2008 by Fuller et al and critiqued in 2009 by
Mistlberger et al. Fuller et al have responded to the critique with new information. Here we
update our critique in the light of this new information. We also identify and correct factual
and conceptual errors in the Fuller et al response. We conclude that the original results of …