From fat to bilayers: Understanding where and how vitamin E works
J Atkinson, D Marquardt, M DiPasquale… - Free Radical Biology and …, 2021 - Elsevier
Free Radical Biology and Medicine, 2021•Elsevier
Vitamin E was one of the last fat-soluble vitamins to be discovered. We provide here an
historical review of the discovery and the increasingly more detailed understanding of the
role of α-tocopherol both as an antioxidant and as a structural component of phospholipid
bilayer membranes. Despite the detailed descriptions now available of the orientation,
location, and dynamics of α-tocopherol in lipid bilayers, there are still gaps in our knowledge
of the effect of α-tocopherol and its potential receptors than control gene transcription.
historical review of the discovery and the increasingly more detailed understanding of the
role of α-tocopherol both as an antioxidant and as a structural component of phospholipid
bilayer membranes. Despite the detailed descriptions now available of the orientation,
location, and dynamics of α-tocopherol in lipid bilayers, there are still gaps in our knowledge
of the effect of α-tocopherol and its potential receptors than control gene transcription.
Abstract
Vitamin E was one of the last fat-soluble vitamins to be discovered. We provide here an historical review of the discovery and the increasingly more detailed understanding of the role of α-tocopherol both as an antioxidant and as a structural component of phospholipid bilayer membranes. Despite the detailed descriptions now available of the orientation, location, and dynamics of α-tocopherol in lipid bilayers, there are still gaps in our knowledge of the effect of α-tocopherol and its potential receptors than control gene transcription.
Elsevier
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