Functional characterization and overexpression of Δ12-desaturase in the oleaginous yeast Rhodotorula toruloides for production of linoleic acid-rich lipids
Linoleic acid (LA) has garnered much attention due to its potential applications in the
oleochemical and nutraceutical industries. The oleaginous yeast Rhodotorula toruloides has
outstanding lipogenecity, and is considered a potential alternative to the current plant-based
platforms for LA production. Δ12-fatty acid desaturases (Δ12-Fads) are involved in LA
synthesis in various fungi and yeasts, but their functions in R. toruloides remain poorly
understood. To achieve the production of LA-rich lipids in R. toruloides, we investigated the …
oleochemical and nutraceutical industries. The oleaginous yeast Rhodotorula toruloides has
outstanding lipogenecity, and is considered a potential alternative to the current plant-based
platforms for LA production. Δ12-fatty acid desaturases (Δ12-Fads) are involved in LA
synthesis in various fungi and yeasts, but their functions in R. toruloides remain poorly
understood. To achieve the production of LA-rich lipids in R. toruloides, we investigated the …
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