Functional impact of white matter hyperintensities in cognitively normal elderly subjects

ME Murray, ML Senjem, RC Petersen… - Archives of …, 2010 - jamanetwork.com
Objective To investigate the impact white matter hyperintensities (WMH) detected on
magnetic resonance imaging have on motor dysfunction and cognitive impairment in elderly
subjects without dementia. Design Cross-sectional study. Setting Population-based study on
the incidence and prevalence of cognitive impairment in Olmsted County, Minnesota.
Participants A total of 148 elderly subjects (65 men) without dementia ranging in age from 73
to 91 years. Main Outcome Measures We measured the percentage of the total white matter …
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