Functional polymorphisms in the CD44 gene and acute myeloid leukemia cancer risk in a Chinese population
CD44 is such one adhesion molecule that mediates interactions between acute myeloid
leukemia (AML) cells and stromal. It has been demonstrated that CD4 plays a critical role in
AML development. However, studies of functional single nucleotide polymorphisms (SNPs)
in CD44 gene have not touched upon AML. This case–control study probed the contribution
of functional SNPs in CD44 gene to AML susceptibility in eastern Chinese population. Five
representative SNPs of CD44 (rs10836347C> T, rs13347C> T, rs1425802A> G …
leukemia (AML) cells and stromal. It has been demonstrated that CD4 plays a critical role in
AML development. However, studies of functional single nucleotide polymorphisms (SNPs)
in CD44 gene have not touched upon AML. This case–control study probed the contribution
of functional SNPs in CD44 gene to AML susceptibility in eastern Chinese population. Five
representative SNPs of CD44 (rs10836347C> T, rs13347C> T, rs1425802A> G …
Functional polymorphisms in the CD44 gene and acute myeloid leukemia cancer risk in a Chinese population.
WHC Wu HongChun, DJQ Deng JieQiong… - 2015 - cabidigitallibrary.org
CD44 is such one adhesion molecule that mediates interactions between acute myeloid
leukemia (AML) cells and stromal. It has been demonstrated that CD4 plays a critical role in
AML development. However, studies of functional single nucleotide polymorphisms (SNPs)
in CD44 gene have not touched upon AML. This case-control study probed the contribution
of functional SNPs in CD44 gene to AML susceptibility in eastern Chinese population. Five
representative SNPs of CD44 (rs10836347C> T, rs13347C> T, rs1425802A> G, rs11821102 …
leukemia (AML) cells and stromal. It has been demonstrated that CD4 plays a critical role in
AML development. However, studies of functional single nucleotide polymorphisms (SNPs)
in CD44 gene have not touched upon AML. This case-control study probed the contribution
of functional SNPs in CD44 gene to AML susceptibility in eastern Chinese population. Five
representative SNPs of CD44 (rs10836347C> T, rs13347C> T, rs1425802A> G, rs11821102 …
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