Fungal biofilms and antimycotics

J Chandra, G Zhou, MA Ghannoum - Current Drug Targets, 2005 - ingentaconnect.com
… between antifungal resistance and ECM of fungal biofilms. In one of the early studies, the
contribution of ECM to antifungal resistance of C. albicans biofilms was investigated by deter- …

Antifungal therapy with an emphasis on biofilms

CG Pierce, A Srinivasan, P Uppuluri… - Current opinion in …, 2013 - Elsevier
… For example, both Hsp90 and calcineurin inhibitors may be able to overcome resistance
when used in combination with antifungals [54, 55], and DNAse treatment improves the anti-…

Reactive oxygen species-inducing antifungal agents and their activity against fungal biofilms

N Delattin, BPA Cammue, K Thevissen - Future medicinal chemistry, 2014 - Future Science
… of antimycotics and novel antifungal compounds that induce ROS in fungal planktonic and
biofilm … enhance the antibiofilm activity of such ROS-inducing antimycotics will be discussed. …

Fungal Biofilms:In Vivo Models for Discovery of Anti‐Biofilm Drugs

JE Nett, DR Andes - Microbial Biofilms, 2015 - Wiley Online Library
… This model has been adapted for use in a rat, a rabbit, and a mouse and has been
instrumental for examining the efficacy of antifungals against biofilms formed in vivo …

[HTML][HTML] Fungal biofilms

S Fanning, AP Mitchell - PLoS pathogens, 2012 - journals.plos.org
… emphasize common features among fungal biofilms, and point … Biofilm cell communities
are more resistant to antifungal drugs than planktonic cells. Contributing factors include biofilm

[PDF][PDF] Biofilms and antifungal resistance

EP Fox, SD Singh-Babak, N Hartooni… - Antifungals: From …, 2015 - researchgate.net
… the biofilmforming capabilities of other fungalfungal species have now been described as
forming biofilms both in vitro and in vivo, and we will discuss examples of these fungal biofilm-…

Strength in numbers: antifungal strategies against fungal biofilms

G Ramage, SN Robertson, C Williams - International journal of antimicrobial …, 2014 - Elsevier
… with the biofilm lifestyle. This review will summarise some of the key fungal biofilm-forming …
Penetration of antifungals through the biofilm is a major obstacle, with the ECM effectively …

[HTML][HTML] Fungal biofilms and drug resistance

MA Jabra-Rizk, WA Falkler… - Emerging infectious …, 2004 - ncbi.nlm.nih.gov
biofilms include those occurring on devices such as indwelling intravascular catheters.
Fungal biofilm-… Biofilm-associated Candida show uniform resistance to a wide spectrum of the …

[HTML][HTML] Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms

P Van Dijck, J Sjollema, BPA Cammue, K Lagrou… - Microbial Cell, 2018 - ncbi.nlm.nih.gov
antimycotics, we propose to use the abbreviation ‘IC 50 or IC 90 ’, defined as the minimum
inhibitory concentration of the agent or standard antimycotic that inhibits growth of the fungus (…

Interaction of Candida albicans Biofilms with Antifungals: Transcriptional Response and Binding of Antifungals to Beta-Glucans

G Vediyappan, T Rossignol… - Antimicrobial agents and …, 2010 - Am Soc Microbiol
… Since we aimed to assess the transcriptional responses of biofilms early after antifungal
exposure, 30 h-biofilms exposed for 0 min, 30 min, 60 min, or 120 min to 8 μg/ml AMB, 80 μg/ml …