… To evaluate the susceptibilities of fungal cells in mature biofilms, cryptococcal biofilms were
incubated with antifungal drugs and metabolic activity was measured by the XTT reduction …

… Recalcitrance to antifungal therapy remains the greatest threat to patients with fungal biofilms…
understanding of the basic biology and clinical implications associated with fungal biofilms. …

… were resistant to the high levels of amphotericin B and different azole antifungals [95].
Nevertheless, factors including pH, temperature, oxygen availability, and other environmental …

… [74,75,76]: (i) EPM acts as a physical barrier, preventing the entry of antifungals to biofilms,
by either slowing drug diffusion or through specific sequestration mechanisms [74], with EPM …

… -specific drugs in the market that effectively treat biofilm … of fungal biofilms to standard
antifungal drugs is complex and multifactorial. Biofilms provide physical protection from antifungal …

… first successful application to a study of fungal biofilms. A complex network of yeasts and
hyphae was generated on each cellulose membrane; these biofilms lacked the overall depth of …

… albicans will help to solve the puzzle of biofilm resistance to antifungals, and the method of
isolating persisters reported in this study provides a powerful tool to search for persister genes…

… biofilm matrix, the presence of persister cells, the antifungal resistance gene expression and
the increase of sterols on the membrane of biofilm … species biofilm antifungal resistance and …

… facilitates filamentous fungal cell survival in the presence of high-dose antifungals (40). …
fungal biofilms and facilitate fungal survival in the face of contemporary antifungal therapies. …

… it forms the foundation for all other pathogenic fungal biofilm studies, that is, understanding
the … This review will examine where fungal biofilms are clinically important, discuss why these …