Gamma tocopherol-enriched supplement reduces sputum eosinophilia and endotoxin-induced sputum neutrophilia in volunteers with asthma
AJ Burbank, CG Duran, Y Pan, P Burns, S Jones… - Journal of Allergy and …, 2018 - Elsevier
Background We and others have shown that the gamma tocopherol (γT) isoform of vitamin E
has multiple anti-inflammatory and antioxidant actions and that γT supplementation reduces
eosinophilic and endotoxin (LPS)-induced neutrophilic airway inflammation in animal
models and healthy human volunteers. Objective We sought to determine whether γT
supplementation reduces eosinophilic airway inflammation and acute neutrophilic response
to inhaled LPS challenge in volunteers with asthma. Methods Participants with mild asthma …
has multiple anti-inflammatory and antioxidant actions and that γT supplementation reduces
eosinophilic and endotoxin (LPS)-induced neutrophilic airway inflammation in animal
models and healthy human volunteers. Objective We sought to determine whether γT
supplementation reduces eosinophilic airway inflammation and acute neutrophilic response
to inhaled LPS challenge in volunteers with asthma. Methods Participants with mild asthma …
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