Ganciclovir

CS Crumpacker - New England Journal of Medicine, 1996 - Mass Medical Soc
ganciclovir's mechanisms of action and resistance and discuss the clinical effectiveness of
intravenous and oral ganciclovir… of ganciclovir and acyclovir, large amounts of ganciclovir

Ganciclovir

AA Al-Badr, TDS Ajarim - Profiles of drug substances, excipients and …, 2018 - Elsevier
Ganciclovir is given by intravenous infusion as the sodium salt but doses are expressed in
terms ganciclovir 54.3 mg of ganciclovir sodium is equivalent to about 50 mg of ganciclovir. …

Antiviral activity and mechanism of action of ganciclovir

T Matthews, R Boehme - Reviews of infectious diseases, 1988 - academic.oup.com
ganciclovir-MP- is rate-limiting for the synthesis of ganciclovir-TP. Subsequent phosphorylating
reactions-producing ganciclovir-DP and ganciclovir… significant amounts of ganciclovir-MP …

Ganciclovir: a review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in cytomegalovirus infections

D Faulds, RC Heel - Drugs, 1990 - Springer
… maintenance therapy to prevent disease progression, as ganciclovir (like other antivirals) …
frequently during ganciclovir administration but are usually reversible. Ganciclovir has not …

Ganciclovir for the treatment and suppression of serious infections caused by cytomegalovirus

…, SA Spector, Ganciclovir Study Group - The American journal of …, 1987 - Elsevier
Ganciclovir is a congener of acyclovir with in vitro activity against cytomegalovirus. Ninety-seven
patients with the acquired immune deficiency syndrome (AIDS) and a serious …

Ganciclovir: an update of its therapeutic use in cytomegalovirus infection

A Markham, D Faulds - Drugs, 1994 - Springer
… Direct comparisons between ganciclovir and foscarnet in this indication are few… ganciclovir;
maintenance therapy does not appear to be required in these latter 2 indications. Ganciclovir

Oral ganciclovir for patients with cytomegalovirus retinitis treated with a ganciclovir implant

…, Roche Ganciclovir Study Group - … England Journal of …, 1999 - Mass Medical Soc
… in the group assigned to the ganciclovir implant plus placebo, as … ganciclovir implant plus
oral ganciclovir (P=0.002) and 19.6 percent in the group assigned to intravenous ganciclovir

Pharmacokinetic, safety, and antiviral profiles of oral ganciclovir in persons infected with human immunodeficiency virus: a phase I/II study

SA Spector, DF Busch, S Follansbee… - Journal of Infectious …, 1995 - academic.oup.com
A phase I/II study evaluated the pharmacokinetics, tolerability, and antiviral activity of oral
ganciclovir in persons infected with human immunodeficiency virus (HIV). Oral bioavailability …

Ganciclovir treatment of symptomatic congenital cytomegalovirus infection: results of a phase II study

RJ Whitley, G Cloud, W Gruber… - Journal of Infectious …, 1997 - academic.oup.com
… A phase II evaluation was done of ganciclovir for the … Five additional babies received
ganciclovir on a compassionate plea … safety evaluation of ganciclovir for the treatment of symptom…

Treatment of cytomegalovirus retinitis with a sustained-release ganciclovir implant

…, Ganciclovir Implant Study Group - … England Journal of …, 1997 - Mass Medical Soc
… with intravenous ganciclovir as among those treated with a ganciclovirganciclovir than
with a ganciclovir implant (risk ratio, 0.5; P = 0.19). Patients treated with intravenous ganciclovir