… treatments, thus robustly activating several pro-apoptotic pathways, and paving the way for
… therapeutically beneficial application of pro-apoptotic gene therapy for cancer of the breast. …

… treatments, thus robustly activating several pro-apoptotic pathways, and paving the way for
… therapeutically beneficial application of pro-apoptotic gene therapy for cancer of the breast. …

… The results of this study, the first targeted gene therapy for breast cancer and the first to use
… of genetic prodrug activation therapies that exploit the transcriptional profile of cancer cells. …

… be secreted and function in the excellular compartment or by re-entering the cells.61, 62 In
terms of cancer gene therapy, a chimeric pro-apoptotic protein can be generated by fusing a …

… combined endostatin and TRAIL gene therapy and provide a promising application prospect
by virtue of adenovirus-mediated anti‑angiogenic and pro‑apoptotic cancer gene therapy. …

… Pro-apoptotic factors are indicated in italic, and antiapoptotic factors are indicated in bold.
The antiapoptotic factors Bcl-2 and Bcl-Xl inhibit mitochondrial-mediated apoptosis. In type II …

… )-mediated p53 gene therapy (p53 Ad) and paclitaxel (Taxol) in a panel of human tumor cell
lines… Paclitaxel had synergistic or additive efficacy with p53 gene therapy. In no case was the …

… The combination of tumor selective pro-apoptotic activity with anti-angiogenic properties
qualifies mda-7 as a prospective agent for cancer gene therapy. Introgen Therapeutics, Inc. …

… represent valuable tools for cancer gene therapy in the future. … genes is a straightforward
strategy for cancer gene therapy. First, it is now known that most, if not all, anticancer treatments …

… The ratio of pro-apoptotic (PAP) and anti-apoptotic (AAP) bcl-2 proteins is important in …
death in mesothelioma when combined with adenoviral pro - apoptotic gene therapy ( PAGT ) by …