Genetic ancestry of 1127 Brazilian breast cancer patients and its correlation with molecular subtype and geographic region
RA da Costa Vieira, D Sant'Anna, AC Laus… - Clinical Breast …, 2023 - Elsevier
Purpose Breast cancer molecular subtypes show significant differences in different ethnic
groups in the United States, but no study has evaluated genetic ancestry in breast cancer in
Brazilian women. Methods Breast cancer patients from distinct parts of Brazil were
evaluated. Molecular subtypes were determined by immunohistochemistry. Genetic ancestry
was evaluated using a panel of 46 AIMs (ancestry informative markers), which classified
genetic ancestry as European, African, Asian, and Amerindian. PCR products were …
groups in the United States, but no study has evaluated genetic ancestry in breast cancer in
Brazilian women. Methods Breast cancer patients from distinct parts of Brazil were
evaluated. Molecular subtypes were determined by immunohistochemistry. Genetic ancestry
was evaluated using a panel of 46 AIMs (ancestry informative markers), which classified
genetic ancestry as European, African, Asian, and Amerindian. PCR products were …
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