38 天前 - … susceptibility are under intense investigation, with APOE being the major genetic
risk factor for late onset AD. Yet the impact of unique risk factors on brain networks is difficult to …

39 天前 - … Background: Alzheimer's disease (AD), particularly its late-onset form (LOAD), is a
… suggests that genetic variations in TOMM40 rs20675650 are associated with susceptibility to …

40 天前 - … Since biological aging also may impact the age of onset, exploring the differences
in its effects on young-onset and late-onset dementia is valuable, but to our knowledge, no …

49 天前 - … ) mice, also referred to as a model of late-onset AD in previous literature], we identified
… putative causal factors for AD. Our results indicate that genetic predisposition and aging…

53 天前 - … Polygenic risk scores (PRSs) for schizophrenia and AD indicate some genetic
predisposition, … delusional disorder and AD, and genetic relationships between AD and late-onset …

109 天前 - … causal association between RA and late-onset (LO) AD (OR [… Alzheimer's disease;
(B) Late-onset Alzheimer's disease; (… The leave-one-out sensitivity test identified the genetic …

113 天前 - … ’s disease (PD) has been identified as a genetically … sleep disorders in the PD
group, especially in the late-onset … of the NEK1 gene that affect PD susceptibility in this study. …

115 天前 - … Susceptibility to Alzheimer’s disease depends on a combination of … are the major
genetic risk factor for late-onset Alzheimer’s disease (LOAD), mutations in genes such as …

123 天前 - … While the study of risk factors for late-onset dementia has yielded some significant
… the causes of early-onset dementia. Hypothesized risk factors include genetic predisposition, …

140 天前 - … : Genetic susceptibility is a primary factor contributing to etiology of late-onset
Alzheimer's disease … widely recognized as the predominant genetic factor influencing LOAD. It has …