Genetic risk factors for idiopathic urolithiasis: a systematic review of the literature and causal network analysis

K Taguchi, T Yasui, DS Milliner, B Hoppe, T Chi - European urology focus, 2017 - Elsevier
Context Urolithiasis has a high prevalence and recurrence rate. Prevention is key to patient
management, but risk stratification is challenging. In particular, genetic predisposition for
urinary stones is not fully understood. Objective To review current evidence of potential
causative genes for idiopathic urolithiasis and map their relationships to one another. This
evidence is essential for future establishment of molecular targeted therapy. Evidence
acquisition A systematic literature review from 2007 to 2017 was performed in accordance …
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