Objective The objective of this study was to identify genetic variants associated with
angiotensin-converting enzyme (ACE) inhibitor-associated angioedema. Participants and
methods We carried out a genome-wide association study in 175 individuals with ACE
inhibitor-associated angioedema and 489 ACE inhibitor-exposed controls from Nashville
(Tennessee) and Marshfield (Wisconsin). We tested for replication in 19 cases and 57
controls who participated in Ongoing Telmisartan Alone and in Combination with Ramipril …