Aspects of the present disclosure relates to genetically altered LysM receptors. In particular,
the present disclosure relates to a hydrophobic patch into the LysM2 domain which can
increase affinity and/or selectivity for LCOs and by replacement of regions in the LysM1
domain with the corresponding regions of the LysM1 domain from a donor LysM receptor
that can alter the affinity and/or selectivity for the oligosaccharide particularly for LCOs and
can alter the specificity between LCO when using regions from a high affinity and specificity …