[HTML][HTML] Genome-wide association study identifies 30 obsessive-compulsive disorder associated loci

NI Strom, ZF Gerring, M Galimberti, D Yu… - medRxiv, 2024 - ncbi.nlm.nih.gov
Obsessive-compulsive disorder (OCD) affects~ 1% of the population and exhibits a high
SNP-heritability, yet previous genome-wide association studies … mechanisms of the disorder. We …

Genome-wide association study of obsessive-compulsive disorder

SE Stewart, D Yu, JM Scharf, BM Neale… - Molecular …, 2013 - nature.com
… analyses for quantitative trait loci (QTLs) among genome-wide association study (GWAS) …
of the obsessive-compulsive disorder (OCD)-associated SNPs. The black dot identifies the …

Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS

M Mattheisen, JF Samuels, Y Wang… - Molecular …, 2015 - nature.com
… of child and adolescent OCD probands report prevalence rates of 7–15% in first-degree
relatives, and 20–30% of … Identification of loci associated with schizophrenia by genome-wide

[HTML][HTML] Genome-wide association study identifies new loci associated with OCD

…, M Mattheisen, Related Disorders Consortium… - MedRxiv, 2024 - ncbi.nlm.nih.gov
… ) individuals were below the age of 30, 230,696 (24.81%) between 30 and 45, 257,793 between
… A population-based family clustering study of tic-related obsessive-compulsive disorder. …

Revealing the complex genetic architecture of obsessive-compulsive disorder using meta-analysis

D Posthuma - Molecular psychiatry, 2018 - research.vu.nl
… the Genomic Psychiatry Cohort,30 matched to the OCGAS cases. … the two published
genome-wide association studies of OCD, … Loci nominally associated with autism from …

Genome-Wide Association Study of Obsessive-Compulsive Symptoms including 33,943 individuals from the general population

NI Strom, CL Burton, C Iyegbe, T Silzer… - Molecular …, 2024 - nature.com
… of obsessive-compulsive disorder (OCD), many more (~13–38%) experience subclinical …
above 0 or both below 0), and 30 traits showing a discordant direction of correlation (ie, one …

[PDF][PDF] Genome-wide association study identifies 30 obsessive-compulsive disorder associated loci

M Wagner, JA Zwart, G Breen, G Nestadt, J Kaprio - genepi.qimr.edu.au
… We identified 30 independent SNPs (see Supplementary Note 2 for a definition of … the
genome-wide threshold for significance ( 5 10 ; Manhattan plot in Figure 1, regional association

Genome-wide DNA methylation analysis in obsessive-compulsive disorder patients

W Yue, W Cheng, Z Liu, Y Tang, T Lu, D Zhang… - Scientific reports, 2016 - nature.com
… probes, 2,478 loci were in a promoter-associated region of … genome-wide association study
(GWAS) for OCD with multiethnic samples, which including the DLGAP1, BTBD3 associated

Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD

D Yu, CA Mathews, JM Scharf… - American Journal of …, 2015 - Am Psychiatric Assoc
… with variations in brain gene expression levels (expression quantitative loci, … genome-wide
association studies (GWAS) of Tourette’s syndrome and OCD, and for each disorder identified

[HTML][HTML] The genomics of visuospatial neurocognition in obsessive-compulsive disorder: A preliminary GWAS

M Alemany-Navarro, M Tubío-Fungueiriño… - … of Affective Disorders, 2023 - Elsevier
study of Obsessive-Compulsive Disorder (OCD) genomics has primarily been tackled by
Genome-wide association studies … One hundred thirty-three OCD patients were genotyped with …