Chronic pain is highly prevalent worldwide and represents a significant socioeconomic and
public health burden. Several aspects of chronic pain, for example back pain and a severity-
related phenotype 'chronic pain grade', have been shown previously to be complex heritable
traits with a polygenic component. Additional pain-related phenotypes capturing aspects of
an individual's overall sensitivity to experiencing and reporting chronic pain have also been
suggested as a focus for investigation. We made use of a measure of the number of sites of …

Chronic pain is highly prevalent worldwide, contributing a significant socioeconomic and
public health burden. Several aspects of chronic pain, for example back pain and a severity-
related phenotype, chronic pain grade, have been shown to be complex, heritable traits with
a polygenic component. Additional pain-related phenotypes capturing aspects of an
individual's overall sensitivity to experiencing and reporting chronic pain have also been
suggested. We have here made use of a measure of the number of sites of chronic pain in …