Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer

AP Klein, BM Wolpin, HA Risch… - Nature …, 2018 - nature.com
PANcreatic Disease ReseArch (PANDoRA) consortium 23 . In a combined meta-analysis
of up to 11,537 pancreatic cancer … , we identified three additional loci of genome-wide

Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer

BM Wolpin, C Rizzato, P Kraft, C Kooperberg… - Nature …, 2014 - nature.com
genome-wide significance located 455 kb telomeric of PVT1. Our study identified multiple new
susceptibility alleles for pancreatic … A Manhattan plot for the results of the meta-analysis of …

Pathway analysis of genome-wide association study data highlights pancreatic development genes as susceptibility factors for pancreatic cancer

D Li, EJ Duell, K Yu, HA Risch, SH Olson… - …, 2012 - academic.oup.com
Genome-wide association studies (GWAS) have become the standard for … cancer. Two
GWAS (PanScan 1 and PanScan 2) recently identified four susceptibility loci for pancreatic cancer

Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer

Y Lin, M Nakatochi, Y Hosono, H Ito, Y Kamatani… - Nature …, 2020 - nature.com
… Therefore, the role of common susceptibility loci in East Asian populations remains … To
detect additional susceptibility loci for pancreatic cancer, we perform a meta-analysis combining …

A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer

E López de Maturana, JA Rodríguez, L Alonso, O Lao… - Genome medicine, 2021 - Springer
… In comparison with other major cancers, fewer genome-wide … in the Discovery phase, we
performed a meta-analysis using … approach to identify novel PC genetic susceptibility loci, we …

A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22. 1, 1q32. 1 and 5p15. 33

GM Petersen, L Amundadottir, CS Fuchs, P Kraft… - Nature …, 2010 - nature.com
… the CLPTM1L-TERT locus on 5p15.33, which is associated with multiple cancers. Our study
has identified common susceptibility loci for pancreatic cancer that warrant follow-up studies. …

[HTML][HTML] Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32. 1, 5p15. 33 and 8q24. 21

M Zhang, Z Wang, O Obazee, J Jia, EJ Childs… - Oncotarget, 2016 - ncbi.nlm.nih.gov
genome-wide significance for pancreatic cancer risk. … meta-analysis to combine association
results for a total of 5,107 … pancreatic cancer susceptibility locus [12]. Multiple independent …

Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations

C Wu, X Miao, L Huang, X Che, G Jiang, D Yu… - Nature …, 2012 - nature.com
… The ORs of meta-analysis of discovery (additive model) and replication (additive model)
are … In conclusion, we have identified five new susceptibility loci for pancreatic cancer in the …

A transcriptome-wide association study identifies novel candidate susceptibility genes for pancreatic cancer

J Zhong, A Jermusyk, L Wu, JW Hoskins… - … the National Cancer …, 2020 - academic.oup.com
… Although 20 pancreatic cancer susceptibility loci have been identified through genome-wide
association studies in individuals of European ancestry, much of its heritability remains …

Pancreatic cancer susceptibility loci and their role in survival

C Rizzato, D Campa, N Giese, J Werner… - PloS one, 2011 - journals.plos.org
… , a genome-wide association study, identified several common polymorphisms affecting
pancreatic cancer susceptibility. … to be associated with pancreatic cancer risk. Moreover the scan …