揭示阿尔茨海默病中的DNA 甲基化: 基于阵列的人脑研究综述

VC Alves, E Carro, J Figueiro-Silva - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… brain regions reveals distinctive DNA methylation patterns … the gold standard for the
genome-wide mapping of 5mC at … of this review, only the most prevalent top 10 DMPs or DMRs, …

脑组织的表达数量性状遗传位点定位方法解析精神疾病遗传基础

C Liu - Neuroscience Bulletin, 2011 - Springer
… that the common disease/common variant model, on which the … the human brain carries
more tissue-specific alternative splicing … Genome-wide survey of human alternative premRNA …

正常组织与肿瘤组织中总体5hmC 和5mC 水平的变化程度与结直肠癌肿瘤发生及预后有关

Y Tian, A Lin, M Gan, H Wang, D Yu, C Lai… - Journal of Zhejiang …, 2017 - Springer
… Aberrant DNA methylation has raised widespread attention … In this study, we used ELISA
to quantify the genomewide 5hmC … activated in cancer are tissue-specific, and encode tumor-…

[HTML][HTML] 增强子调控异常与恶性肿瘤的关系研究进展

汪徐春, 孙玉洁 - 南京医科大学学报(自然科学版), 2023 - jnmu.njmu.edu.cn
… A tissuespecific transcription enhancer element is located … means of enhancer identification
and common databases. … 基因组关联研究(genomewide association study,GWAS) [21] …

非CpG 甲基化降低是脊髓损伤后重要的表观遗传靶点

Z Wu, C Li, R Zhu, Y Cao, TC Chen… - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
… work elucidated the dynamic pattern of DNA methylation in the … Many studies have
revealed genome-wide genetic or … representation bisulfite sequencing reveals tissue-specific

利用基因组数据挖掘对人类长非编码RNA 进行功能注释

BL Gudenas, J Wang, S Kuang, A Wei… - Journal of Zhejiang …, 2019 - Springer
… The advent of high-throughput technologies allowed the genome-wide detection of …
common features, including being predominantly spliced, expressed at low levels, tissue-specific, …

猪基因组组蛋白修饰H3K27ac 和H3K4me3 图谱和转录组图谱揭示生殖器官特异性活性的转座元件

T Jiang, ZM Zhou, ZQ Ling, Q Zhang, ZZ Wu… - Zoological …, 2024 - zoores.ac.cn
… RNA-seq analysis also revealed widespread expression of TEs … stage-specific and
tissue-specific expression. Of note, 1 967 TE-… and exhibit important tissue-specific biological …

基因组DNA 甲基化及组蛋白甲基化

王瑞娴, 徐建红 - 遗传, 2014 - chinagene.cn
… the research progress of DNA methylation on promoter, gene … Genome-wide high-resolution
mapping and functional … at conserved tissue-specific CpG island shores. Nat Genet, 2009…

MicroRNA 在雷蒙德氏棉中的表达

J Ma, T Guo, Q Wang, K Wang, R Sun… - Journal of Zhejiang …, 2015 - Springer
… We selected 16 miRNAs to profile their tissue-specific expression … , the genome-wide survey
of cotton small RNAs has been conducted using deep sequencing technology. The survey is …

[PDF][PDF] 人类基因组DNA 甲基化数据分析的研究现状

凡时财, 李承哲, 裴云飞 - 中国科学: 生命科学, 2015 - researchgate.net
Tissue-specific demethylation in CpG-poor promoters during … the analysis of genome-wide
DNA methylation profiles. Genome … As the most common type of epigenomic modifications in …