过去一年中添加的文章，按日期排序

Evaluation of homologous recombination repair (HRR) status in metastatic prostate cancer by next-generation sequencing and functional tissue-based …

P Cresta Morgado, S Arce-Gallego, L Delgado-Serrano… - 2024 - ascopubs.org
64 天前 - … the hormone-sensitive (HSPC) (169/219) or castration-resistant (CRPC) (50/219)
setting. Genomic profiling was obtained for 181/219 samples (Panel n=139, WES n=80, both n…
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Repeat Next-Generation Sequencing Testing on Progression in Men With Metastatic Prostate Cancer Can Identify New Actionable Alterations

JJ Park, A Chu, J Li, A Ali, RR McKay… - JCO Precision …, 2024 - ascopubs.org
118 天前 - … in the metastatic castration-resistant prostate cancer setting can … -genomic database,
we provide data on the prevalence of testing and results using tissue and plasma samples …
被引用次数：1 相关文章 所有 4 个版本

Abstract LB196: An atlas of accessible chromatin in advanced prostate cancer

R Shrestha, LN Chesner, M Zhang, S Zhou, A Foye… - Cancer Research, 2024 - AACR
118 天前 - … of patients with metastatic castration-resistant prostate cancer (… samples from the
SU2C/PCF West Coast Prostate Cancer … We comprehensively examined genome-wide TF …
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Real-World Overall Survival and Treatment Patterns by PTEN Status in Metastatic Castration-Resistant Prostate Cancer

S Gupta, TM To, R Graf, EE Kadel III, N Reilly… - JCO Precision …, 2024 - ascopubs.org
126 天前 - … Comprehensive genomic profiling (CGP) of tumor specimens was performed using
next-generation sequencing. First-line (1L) and second-line (2L) treatment patterns were …
相关文章 所有 3 个版本

Integrated analysis of cfDNA fragmentomics, DNA methylation and cfRNA transcription in metastatic castration-resistant prostate cancer (mCRPC)

C Dai, L Zhu, Y Huang, G Bonora, K Zhou, S Jia, P Du - Cancer Research, 2024 - AACR
132 天前 - … We conducted a comprehensive profiling of cfDNA fragmentomics, … genome-wide
DNA methylation on two metastatic castration-resistant prostate cancer (mCRPC) samples to …
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Liquid biopsy for prostate cancer molecular characterization: homologous recombination system and genomic profile

A Virga - 2024 - amsdottorato.unibo.it
133 天前 - … prostate cancer (PCa). Treatment with PARP inhibitors (PARPi) has recently been
introduced for metastatic castration-resistant … score of 63 in 2 samples with double alterations, …
相关文章 所有 2 个版本

Circulating tumour DNA as a comprehensive multi-omic tool for profiling advanced prostate cancer

C Herberts - 2024 - open.library.ubc.ca
133 天前 - … genomic vulnerabilities are now standard-of-care in metastatic castration-resistant
prostate cancer … deleterious rearrangements in BRCA2-defective samples but via (negative-…
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Abstract PR005: Tracing the clonal dynamic of metastatic castration-resistant prostate cancer over immunotherapy using circulating tumor DNA

C Li, A Baj, CCY Seo, NT Terrigino, JR Bright… - Cancer Research, 2024 - AACR
182 天前 - … that tumor clones that are responsible for therapy resistance carry distinct genomic
profiles, … cfDNA samples with a tumor fraction of lower than 10% were excluded. Various …
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Nucleosome profiling at AR binding sites (ARBS) to provide a prognostic tool for metastatic castration-resistant prostate cancer (mCRPC).

C Dai, L Zhu, H Fettke, S Gan, P Du, S Jia, A Azad - 2024 - ascopubs.org
185 天前 - … (low-pass whole genome sequencing, LP-WGS), we profiled cfDNA fragment
coverage … patient samples, we quantified sample-level ARBS nucleosome profiling abnormality …
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… ) expression as a potential predictive biomarker for response to androgen receptor signaling inhibitor (ARSI) therapy in metastatic castration-resistant prostate cancer  …

X Zhu, DJ Vis, M Sjöström, R Shrestha, J Kneppers… - 2024 - ascopubs.org
185 天前 - … Known resistance mechanisms include genetic alterations … , we compared the
RNA-seq profiles of paired metastatic … The patient samples were obtained from two independent …
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