Genomic tools for environmental epigenetics and implications for public health

BPU Perera, LK Svoboda, DC Dolinoy - Current opinion in toxicology, 2019 - Elsevier
Epigenetics refers to the study of mitotically heritable and potentially reversible changes in
gene expression unrelated to the DNA sequence itself, influenced by epigenetic marks
including chromatin modifications, noncoding RNA (ncRNA), and alterations to DNA itself
via methylation and hydroxymethylation. Epigenetics has taken center stage in the study of
diseases such as cancer, diabetes, and neurodegeneration; however, its integration into the
field of environmental health sciences and toxicology (eg toxicoepigenetics) is in its infancy …
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