Genotoxicity of dithiocarbamates and their metabolites

J Franekić, N Bratulić, M Pavlica, D Papeš - Mutation Research Letters, 1994 - Elsevier
Dithicarbamate fungicides are widely used in agriculture for protection of vegetable crop and
seeds. The mutagenicity spectra of ziram, thiram, zineb S-65 and ETU were determined by
employing a battery of test systems included the bacterium Salmonella typhimurium (strain
TA98, TA100, TA102, TA104, TA1535, TA1538), the yeast Saccharomyces cerevisiae (strain
D61. M) and the shallot Allium ascalonicum somatic cells. Plate incorporation assay with S.
typhimurium demonstrated direct mutagenicity of ziram in TA100 and thiram in TA100 and …
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