Granulocyte colony stimulating factor therapy for acute myocardial infarction

K Moazzami, A Roohi… - Cochrane Database of …, 2013 - cochranelibrary.com
Cochrane Database of Systematic Reviews, 2013cochranelibrary.com
Background Acute myocardial infarction (AMI) is the leading cause of death in developed
countries, and current treatment modalities have failed to regenerate the dead myocardium
resulting from the ischemic damage. Stem cells have the potential to regenerate the
damaged myocardium. These cells can be mobilized from the bone marrow by factors such
as granulocyte colony stimulating factor (G‐CSF). Objectives To assess the effects of stem
cell mobilization following granulocyte colony stimulating factor therapy in patients with …
Background
Acute myocardial infarction (AMI) is the leading cause of death in developed countries, and current treatment modalities have failed to regenerate the dead myocardium resulting from the ischemic damage. Stem cells have the potential to regenerate the damaged myocardium. These cells can be mobilized from the bone marrow by factors such as granulocyte colony stimulating factor (G‐CSF).
Objectives
To assess the effects of stem cell mobilization following granulocyte colony stimulating factor therapy in patients with acute myocardial infarction.
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