Objectives Late-life major depression (LLD) is characterized by distinct epidemiologic and
psychosocial factors, as well as medical comorbidities that are associated with specific
neuroanatomical differences. The purpose of this study was to use interregional correlations
of cortical and subcortical volumes to examine cortical-subcortical structural network
properties in subjects with LLD compared with healthy comparison subjects. Methods This
was a cross-sectional neuroimaging study conducted in the general community. We …