Both human and animal studies support the relationship between depression and reward
processing abnormalities, giving rise to the expectation that neural signals of these
processes may serve as biomarkers or mechanistic treatment targets. Given the great
promise of this research line, we scrutinized those findings and the theoretical claims that
underlie them. To achieve this, we applied the framework provided by classical work on
causality as well as contemporary approaches to prediction. We identified a number of …