Growth hormone improves body composition, fasting blood glucose, glucose tolerance and liver triacylglycerol in a mouse model of diet-induced obesity and type 2 …
EO List, AJ Palmer, DE Berryman, B Bower, B Kelder… - Diabetologia, 2009 - Springer
Aims/hypothesis Growth hormone has been used experimentally in two studies to treat
individuals with type 2 diabetes, with both reporting beneficial effects on glucose
metabolism. However, concerns over potential diabetogenic actions of growth hormone
complicate its anticipated use to treat type 2 diabetes. Thus, an animal model of type 2
diabetes could help evaluate the effects of growth hormone for treating this condition.
Methods Male C57BL/6J mice were placed on a high-fat diet to induce obesity and type 2 …
individuals with type 2 diabetes, with both reporting beneficial effects on glucose
metabolism. However, concerns over potential diabetogenic actions of growth hormone
complicate its anticipated use to treat type 2 diabetes. Thus, an animal model of type 2
diabetes could help evaluate the effects of growth hormone for treating this condition.
Methods Male C57BL/6J mice were placed on a high-fat diet to induce obesity and type 2 …
Growth hormone improves body composition, fasting blood glucose, glucose tolerance and liver triacylglycerol in a mouse model of diet induced obesity and type 2 …
P Darmon - Diabetologia Notes de lecture, 2009 - Springer
Aims/hypothesis Growth hormone has been used experimentally in two studies to treat
individuals with type 2 diabetes, with both reporting beneficial effects on glucose
metabolism. However, concerns over potential diabetogenic actions of growth hormone
complicate its anticipated use to treat type 2 diabetes. Thus, an animal model of type 2
diabetes could help evaluate the effects of growth hormone for treating this condition.
Methods Male C57BL/6J mice were placed on a high-fat diet to induce obesity and type 2 …
individuals with type 2 diabetes, with both reporting beneficial effects on glucose
metabolism. However, concerns over potential diabetogenic actions of growth hormone
complicate its anticipated use to treat type 2 diabetes. Thus, an animal model of type 2
diabetes could help evaluate the effects of growth hormone for treating this condition.
Methods Male C57BL/6J mice were placed on a high-fat diet to induce obesity and type 2 …
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