Haptoglobin polymorphism: a novel genetic risk factor for celiac disease development and its clinical manifestations
Abstract Background: Haptoglobin (Hp) α-chain alleles 1 and 2 account for 3 phenotypes
that may influence the course of inflammatory diseases via biologically important differences
in their antioxidant, scavenging, and immunomodulatory properties. Hp1-1 genotype results
in the production of small dimeric, Hp2-1 linear, and Hp2-2 cyclic polymeric haptoglobin
molecules. We investigated the haptoglobin polymorphism in patients with celiac disease
and its possible association to the presenting symptoms. Methods: We studied 712 …
that may influence the course of inflammatory diseases via biologically important differences
in their antioxidant, scavenging, and immunomodulatory properties. Hp1-1 genotype results
in the production of small dimeric, Hp2-1 linear, and Hp2-2 cyclic polymeric haptoglobin
molecules. We investigated the haptoglobin polymorphism in patients with celiac disease
and its possible association to the presenting symptoms. Methods: We studied 712 …
[引用][C] S1256 Haptoglobin Polymorphism: A Novel Genetic Risk Factor for Celiac Disease Development and Its Clinical Manifestations
S1256 Haptoglobin Polymorphism: A Novel Genetic Risk Factor for Celiac Disease
Development and Its Clinical Manifestations … books … S1256 Haptoglobin Polymorphism:
A Novel Genetic Risk Factor for Celiac Disease Development and Its Clinical Manifestations …
Development and Its Clinical Manifestations … books … S1256 Haptoglobin Polymorphism:
A Novel Genetic Risk Factor for Celiac Disease Development and Its Clinical Manifestations …
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