[HTML][HTML] Helicobacter pylori infection synergistic with IL-1β gene polymorphisms potentially contributes to the carcinogenesis of gastric cancer

JB Hong, W Zuo, AJ Wang, NH Lu - International journal of medical …, 2016 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) infection is the most common chronic bacterial infection in the
world and the etiological agent for most gastric cancer (GC). Interleukin-1β (IL-1β) is a potent
proinflammatory cytokine, and its deregulation is closely associated with the tumorigenesis
of several cancers. Recent studies have revealed that the IL-1β-31 and-511T alleles are
closely associated with gastric carcinogenesis due to their roles in the induction of gastric
precancerous lesions and hypochlorhydria. Furthermore, H. pylori infection has a synergistic …

Helicobacter pylori infection synergistic with IL-1β gene polymorphisms potentially contributes to the carcinogenesis of gastric cancer.

HJB Hong JunBo, ZW Zuo Wei, WAJ Wang AnJiang… - 2016 - cabidigitallibrary.org
Helicobacter pylori (H. pylori) infection is the most common chronic bacterial infection in the
world and the etiological agent for most gastric cancer (GC). Interleukin-1β (IL-1β) is a potent
proinflammatory cytokine, and its deregulation is closely associated with the tumorigenesis
of several cancers. Recent studies have revealed that the IL-1β-31 and-511T alleles are
closely associated with gastric carcinogenesis due to their roles in the induction of gastric
precancerous lesions and hypochlorhydria. Furthermore, H. pylori infection has a synergistic …
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