Hematological alterations and splenic T lymphocyte polarization at the crest of snake venom induced acute kidney injury in adult male mice
Snake venom induced acute kidney injury (SAKI) is of great clinical relevance in tropical
countries. Involvement of T cell, a key mediator of AKI and its remission, is least explored in
SAKI. In the present study the in vivo hematological alterations and associated splenic T cell
polarization is probed in order to investigate the immune response at the crest of Russell's
viper venom (RVV) induced AKI in experimental murine model. Based on a dose and time
kinetic study intra muscular injection dose of 20 μg RVV/100 gm body weight of mice and …
countries. Involvement of T cell, a key mediator of AKI and its remission, is least explored in
SAKI. In the present study the in vivo hematological alterations and associated splenic T cell
polarization is probed in order to investigate the immune response at the crest of Russell's
viper venom (RVV) induced AKI in experimental murine model. Based on a dose and time
kinetic study intra muscular injection dose of 20 μg RVV/100 gm body weight of mice and …
Hematological alterations and splenic T lymphocyte polarization at the crest of snake venom induced acute kidney injury in adult male mice.
FN Farhat Nasim, SD Sreyasi Das… - 2017 - cabidigitallibrary.org
Snake venom induced acute kidney injury (SAKI) is of great clinical relevance in tropical
countries. Involvement of T cell, a key mediator of AKI and its remission, is least explored in
SAKI. In the present study the in vivo hematological alterations and associated splenic T cell
polarization is probed in order to investigate the immune response at the crest of Russell's
viper venom (RVV) induced AKI in experimental murine model. Based on a dose and time
kinetic study intra muscular injection dose of 20 µg RVV/100 gm body weight of mice and …
countries. Involvement of T cell, a key mediator of AKI and its remission, is least explored in
SAKI. In the present study the in vivo hematological alterations and associated splenic T cell
polarization is probed in order to investigate the immune response at the crest of Russell's
viper venom (RVV) induced AKI in experimental murine model. Based on a dose and time
kinetic study intra muscular injection dose of 20 µg RVV/100 gm body weight of mice and …
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