High‐refined carbohydrate diet leads to polycystic ovary syndrome-like features and reduced ovarian reserve in female rats

OMS Niño, CS da Costa, KM Torres, JF Zanol… - Toxicology Letters, 2020 - Elsevier
Obesity is associated with several female reproductive complications, such as polycystic
ovary syndrome (PCOS). The exact mechanism of this relationship remains unclear. Few
previous studies using diet containing refined carbohydrate (HCD) leading to obesity have
been performed and it is unclear if HCD is linked with reproductive dysfunctions. In this
investigation, we assessed whether subchronic HCD exposure results in reproductive and
other irregularities. Female rats were fed with HCD for 15 days and metabolic outcomes and …
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