[HTML][HTML] High-density lipoprotein remodeling by phospholipid nanoparticles improves cholesterol efflux capacity and protects from atherosclerosis

VA Kudinov, TI Torkhovskaya, TS Zakharova… - Biomedicine & …, 2021 - Elsevier
The efficiency of cholesterol efflux from cells promoted by high-density lipoproteins (HDLs)
depends on HDL concentration and functional properties. The term “dysfunctional HDL”
describes HDLs with impaired protective properties. Cholesterol efflux capacity (CEC) of
HDL is reduced in patients with atherosclerosis, but the exact mechanisms underlying this
impairment are not well characterized. Enriching HDLs with phospholipids (PLs) improves
CEC. Herein, we assessed the potential of PL nanoparticles in improving HDL functionality …

[引用][C] High-Density Lipoprotein Remodeling by Phospholipid Nanoparticles

VA Kudinov, RI Artyushev - Липиды 2021, 2021 - elibrary.ru
High-Density Lipoprotein Remodeling by Phospholipid NanoparticlesHIGH-DENSITY
LIPOPROTEIN REMODELING BY PHOSPHOLIPID NANOPARTICLES
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