[HTML][HTML] Human microRNA expression in sporadic and FAP-associated desmoid tumors and correlation with beta-catenin mutations
A Cavallini, MT Rotelli, C Lippolis, D Piscitelli… - Oncotarget, 2017 - ncbi.nlm.nih.gov
A Cavallini, MT Rotelli, C Lippolis, D Piscitelli, R Digennaro, C Covelli, N Carella…
Oncotarget, 2017•ncbi.nlm.nih.govDesmoid tumors (DT) are rare, benign, fibroblastic neoplasm with challenging histological
diagnosis. DTs can occur sporadically or associated with the familial adenomatous
polyposis coli (FAP). Most sporadic DTs are associated with β-catenin gene (CTNNB1)
mutations, while mutated APC gene causes FAP disease. microRNAs (miRNAs) are
involved in many human carcinogenesis.
diagnosis. DTs can occur sporadically or associated with the familial adenomatous
polyposis coli (FAP). Most sporadic DTs are associated with β-catenin gene (CTNNB1)
mutations, while mutated APC gene causes FAP disease. microRNAs (miRNAs) are
involved in many human carcinogenesis.
Abstract
Desmoid tumors (DT) are rare, benign, fibroblastic neoplasm with challenging histological diagnosis. DTs can occur sporadically or associated with the familial adenomatous polyposis coli (FAP). Most sporadic DTs are associated with β-catenin gene (CTNNB1) mutations, while mutated APC gene causes FAP disease. microRNAs (miRNAs) are involved in many human carcinogenesis.
ncbi.nlm.nih.gov
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