[HTML][HTML] Humoral and T-cell response to SARS-CoV-2 mRNA vaccine in multiple sclerosis patients: Correlations with DMTs and clinical variables
Disease-modifying therapies (DMTs) can affect vaccine responses in individuals with
multiple sclerosis (MS). We assessed the humoral and T-cell responses following SARS-
CoV-2 mRNA vaccination in MS patients receiving various DMTs. We prospectively enrolled
243 participants, including 113 healthy control subjects and 130 MS patients. Blood samples
for detecting SARS-CoV-2 antibodies were collected at three time points: T0, before the first
vaccine dose; T1, before the second dose; and T2, one month after the second dose. In a …
multiple sclerosis (MS). We assessed the humoral and T-cell responses following SARS-
CoV-2 mRNA vaccination in MS patients receiving various DMTs. We prospectively enrolled
243 participants, including 113 healthy control subjects and 130 MS patients. Blood samples
for detecting SARS-CoV-2 antibodies were collected at three time points: T0, before the first
vaccine dose; T1, before the second dose; and T2, one month after the second dose. In a …
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