Hypothalamic Angptl4/Fiaf is a novel regulator of food intake and body weight

HK Kim, BS Youn, MS Shin, C Namkoong, KH Park… - Diabetes, 2010 - Am Diabetes Assoc
OBJECTIVE The angiopoietin-like protein 4 (Angptl4)/fasting-induced adipose factor (Fiaf) is
known as a regulator of peripheral lipid and glucose metabolism. In the present study, we
investigated the physiological role of Angptl4 in central regulation of body weight
homeostasis. RESEARCH DESIGN AND METHODS Hypothalamic Angptl4 expression
levels were measured using immunoblot assay during feeding manipulation or after
administration of leptin, insulin, and nutrients. The effects of Angptl4 on food intake, body …

Hypothalamic Angptl4/Fiaf is a novel regulator of food intake and body weight.

KHK Kim HyunKyong, YBS Youn ByungSoo… - 2010 - cabidigitallibrary.org
OBJECTIVE: The angiopoietin-like protein 4 (Angptl4)/fasting-induced adipose factor (Fiaf)
is known as a regulator of peripheral lipid and glucose metabolism. In the present study, we
investigated the physiological role of Angptl4 in central regulation of body weight
homeostasis. RESEARCH DESIGN AND METHODS: Hypothalamic Angptl4 expression
levels were measured using immunoblot assay during feeding manipulation or after
administration of leptin, insulin, and nutrients. The effects of Angptl4 on food intake, body …
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