… differentiation may be an important factor that determines the hypoxia-induced regulation of
… pancreatic cancer cells is, at least, due to inactivation of NF-.B and Akt signaling caused by …

… The expression of microRNA‑150 (miRNA‑150) was … in pancreatic cancer samples and in
the hypoxia‑induced CaPan2 … The aggressiveness of a cancer cell is determined by its capacity …

… Furthermore, we demonstrated that the hypoxia-induced … that long-term survivors of
pancreatic cancer have high-quality … leading causes for the aggressive behavior of PDACs and …

… hypoxia-induced PLOD2 expression in PSCs creates a permissive microenvironment for
migration of cancer cells … a crucial role in tumor aggressiveness and therapeutic resistance [2], [3…

… Hypoxia induced HIF-1α expression in a time-dependent manner in … in pancreatic cancer
may in return increase HIF-1α expression and cell aggressiveness in pancreatic cancer cells. …

… Our study together with the study that hypoxia induced expression of ARG2 but not ARG1
in PASMCs suggests that ARG2 is the hypoxia-inducible isoform. [17] It is consistent with our …

… increased expression is due to the activation of hypoxia-driven ROS. In addition, we show
that hypoxia induced … invasive ability and EMT of pancreatic cancer through Hh pathway [40]. …

… pancreatic cancer stellate cells. This may provide another plausible mechanism by which
hypoxia-induced stromal autophagy leads to cancer … resulted in increasing expressions of the …

… HDAC1/MTA1 are a promising therapeutic target in pancreatic carcinoma treatment. … high
expression of HIF-1α protein has been found to be associated with both tumor aggressiveness …

… hypoxia can exacerbate the aggressiveness of tumors, so we … the main drivers of the
hypoxia-induced immunosuppressive … resulted in elevated expression levels of B cells chemokine, …