Highlights What are the main findings? The identification of patients with CAP at high risk for
resistant pathogens is of outstanding clinical interest due to the worse outcome of these
patients. However, the HCAP classification and the scores proposed in literature to identify
resistant pathogens in CAP are overly sensitive, leading to inappropriately broad-spectrum
antibiotic use. What is the implication of the main finding? As suggested by the new
IDSA/ATS guidelines, it is crucial to generate local data concerning DRP in order to identify …

A substantial increase in broad-spectrum antibiotics as empirical therapy in patients with
community-acquired pneumonia (CAP) has occurred over the last 15 years. One of the
driving factors leading to that has been some evidence showing an increased incidence of
drug-resistant pathogens (DRP) in patients from a community with pneumonia, including
methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa.
Research has been published attempting to identify DRP in CAP through the …