Imaging red blood cell dynamics by quantitative phase microscopy

G Popescu, YK Park, W Choi, RR Dasari… - Blood Cells, Molecules …, 2008 - Elsevier
Red blood cells (RBCs) play a crucial role in health and disease, and structural and
mechanical abnormalities of these cells have been associated with important disorders such
as Sickle cell disease and hereditary cytoskeletal abnormalities. Although several
experimental methods exist for analysis of RBC mechanical properties, optical methods
stand out as they enable collecting mechanical and dynamic data from live cells without
physical contact and without the need for exogenous contrast agents. In this report, we …
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