Currently, stem cell donor registries include more than 35 million potential donors worldwide
to provide HLA‐matched stem cell products for patients in need of an unrelated donor
transplant. DKMS is a leading stem cell donor registry with more than 9 million donors from
Germany, Poland, the United States, the United Kingdom, India and Chile. DKMS donors
have donated hematopoietic stem cells more than 80,000 times. Many aspects of donor
registry work are closely related to topics from immunogenetics or population genetics. In …

DKMS is a leading stem cell donor registry with more than 9 million donors. Donor registry
activities share many touch points with topics from immunogenetics or population genetics.
In this two‐part review article, we deal with these aspects of donor registry work by using the
example of DKMS. In the second part of the review, we focus on donor typing of non‐HLA
genes, the impact of donor age, gender and CMV serostatus on donation probabilities, the
identification of novel HLA, KIR and MIC alleles by high‐throughput donor typing, the …