Immunohistochemical analysis of thrombi retrieved during treatment of acute ischemic stroke: does stent-retriever cause intimal damage?
P Singh, S Doostkam, M Reinhard, V Ivanovas… - Stroke, 2013 - Am Heart Assoc
P Singh, S Doostkam, M Reinhard, V Ivanovas, CA Taschner
Stroke, 2013•Am Heart AssocBackground and Purpose—To provide evidence whether mechanical thrombectomy with
stent-retrievers in the treatment of acute ischemic stroke causes intimal damage. Methods—
This study analyzed thrombi retrieved by mechanical thrombectomy from cerebral arteries in
48 consecutive patients with acute ischemic stroke for the presence of endothelial cells
using CD34 antibodies. Results—Of 48 thrombi analyzed, CD34-positive cells were absent
in 20, present as isolated cells in 21, and found in clusters in 7 thrombi. We did not find any …
stent-retrievers in the treatment of acute ischemic stroke causes intimal damage. Methods—
This study analyzed thrombi retrieved by mechanical thrombectomy from cerebral arteries in
48 consecutive patients with acute ischemic stroke for the presence of endothelial cells
using CD34 antibodies. Results—Of 48 thrombi analyzed, CD34-positive cells were absent
in 20, present as isolated cells in 21, and found in clusters in 7 thrombi. We did not find any …
Background and Purpose
To provide evidence whether mechanical thrombectomy with stent-retrievers in the treatment of acute ischemic stroke causes intimal damage.
Methods
This study analyzed thrombi retrieved by mechanical thrombectomy from cerebral arteries in 48 consecutive patients with acute ischemic stroke for the presence of endothelial cells using CD34 antibodies.
Results
Of 48 thrombi analyzed, CD34-positive cells were absent in 20, present as isolated cells in 21, and found in clusters in 7 thrombi. We did not find any subendothelial vessel wall structures.
Conclusions
Our findings suggest that mechanical thrombectomy with stent-retrievers does not cause relevant intimal damage in acute ischemic stroke treatment.
Clinical Trial Registration
URL: http://www.germanctr.de. Unique identifier: DRKS00004695
Am Heart Assoc
以上显示的是最相近的搜索结果。 查看全部搜索结果