11 天前 - … proliferation and infiltration of CAR T-cells thus reducing tumor burden, enhancing
survival and limiting side effects in orthotopic triple-negative breast cancer animal models. …

11 天前 - … metastasis of HER2-positive breast cancer. Due to its compact size… breast
cancer cell line (MDA-MB361), which is derived from brain metastases, alongside the HER2-negative …

11 天前 - … NSCLC (Lewis Lung Cancer), triple negative breast (EMT6), … -1 human Her2+
breast cancer murine xenograft model. Flow … new approach for immunotherapy of cancers. They …

11 天前 - … Background Triple negative breast cancer (TNBC) is the most deadly subtype of
breast cancer. However, only about 20% of TNBC patients respond to immunotherapy. Poor …

11 天前 - … with high unmet medical need, such as urothelial carcinoma (UC), esophageal
cancer, non-small cell lung cancer, or triple-negative breast cancer. Enfortumab vedotin (EV), a …

11 天前 - Background The OXEL study (NCT03487666) is a phase II trial that enrolled patients
with triple-negative breast cancer (TNBC) and residual disease following neoadjuvant …

11 天前 - … Methods We studied VISTA expression in human triple-negative breast cancers,
engineered breast cancer cell lines with VISTA over-expression to model tumors, or VISTA …

11 天前 - … tumor models, including CT26, B16F10, and a genetically engineered mouse model
of MMTV-PyMT triple-negative breast cancer. … -STING pathway for cancer immunotherapy. …

11 天前 - … from breast cancer patients. By illuminating the mechanisms underlying immunotherapy
… of standard-of-care treatment for breast cancer patients. Completion of this project will …

11 天前 - … The aLA vaccine given at DL1 has been tolerable to date when given alone or
concurrently with pembrolizumab in patients treated for TNBC, and when given to healthy …